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Technically speaking you should remove your business logic away from your UI layer and have some sort of Validation Object to validate the data in your presentation layer and then post back the results to your view.
You can customize sizing behaviors when working with derived Data Grid View cell, row, and column types by overriding the Data Grid View Cell. The protected resizing method overloads are designed to work in pairs to achieve an ideal cell height-to-width ratio, avoiding overly wide or tall cells.
For all sizing enumerations, values with names that refer to displayed cells limit their calculations to cells in displayed rows.
With these values, you can limit which cells are used to calculate the preferred sizes.
The enumerations used by sizing properties and methods have similar values for content-based sizing.
You must then call the Auto Resize Columns method to adjust the column widths to the calculated ideal.
For example, you might programmatically resize all columns immediately after loading data, or you might programmatically resize a specific row after a particular cell value has been modified. Get Preferred Width() methods or by calling protected resizing method overloads in a derived Data Grid View control.